Structures and Design in Biomacromolecules - 136093
Will not be given the year
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Lecture |
Exercise |
Laboratory |
Project or Seminar |
House Work |
Weekly Hours |
2 |
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Determination of the grade according to progress during the semester and the submission of the final thesis
Prerequisites
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(
| | Physical Chemistry |
124510
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and
| Metabolic Pathways |
134113
| ) |
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or
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(
| | Physical Chemistry |
124510
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and
| Introduction to Biochemistry and Enzymology |
134019
| ) |
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Linked Courses
| | | | General Genetics |
134020
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Overlapping Courses
| | | | Structure and Function of Macromolecules |
138093
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The Chemistry of Macromolecules, Different Levels of Protein Structure, Mapping the Protein Universe, Principles Forces in Protein Folding, Why Is Double-Stranded Dna Helical, What Came First Protein Sequence Or Structure. Designability Principle. Simulating Macromolecular Structures, Kinetics of Protein Folding. Experimental Methods for Studying Folding. Protein Engineering and Design. in Vitro Evolution of Novel Proteins from Scratch. Principles of Designig Ideal Protein Structures. Disordered Proteins and Natively Unfolded Proteins. the Role of Water in the Structure and Function of Module, Students Should Be Able to:
1.
Understand the Basic Forces That Shape Both Proteins and Nucleic Acids Structure. What Mutations Do for a Protein Structure and How to Go About Designing Them for Specific Purposes.
2.
Understand What Determines Protein Folding and Stability.
3.
Understand the Versatility of Natively Unfolded Proteins - What They Are Good for and Why.
4.
Understand Ab Initio Rational Desig Principles of Protein Form Scratch and from Pre-Existing Folds, Towards Synthetic Biology.
5.
Read and Understnad Current Primary Paper Written on Protein Folding and Design, Sufficiently to Present the Subject Orally and Write a Term Paper on It.
TextbooksPublished | Publisher | Authors | Book |
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1993 | | t.e creighton | proteins: structure and molecular properties |
1998 | | k.e van holde w.c. johnson and p.s. ho | principles of physical biochemistry |
Created in 03/02/2023 Time 05:48:23